Back to results

Imubiosciences

Bioinformatics Software Engineer

Salary not disclosed3+ yearsOnsite

  • London
  • Full time
  • Yesterday
Newly posted

About the role

The Bioinformatics Software Engineer will drive the flow cytometry data engineering infrastructure, annotation pipelines, and model registry operations for a clinical biomarker discovery platform. This role focuses on translating high-dimensional data into reproducible, production-grade features while ensuring compliance with MedDev ML standards. The engineer will manage model lifecycles, enforce data integrity, and collaborate within a multidisciplinary team to support precision medicine development.

Responsibilities

  • Execute automated cell annotation workflows on large-scale cytometry datasets and generate quality-control reports.
  • Establish and lock baseline models and numerical stability criteria for feature extraction pipelines.
  • Manage the formal model lifecycle registry, including versioning, freezing, and locking gating ensembles.
  • Refit machine learning models on expanded cohorts and execute final model freezing prior to clinical evaluations.
  • Ensure full reproducibility by pinning environment specifications and logging all hyperparameters.
  • Serve as a primary code reviewer to enforce strict data leakage controls and modular coding standards.
  • Participate in traceability audits and regulatory compliance verification.

Required skills

  • Python
  • NumPy
  • Pandas
  • SciPy
  • scikit-learn
  • PyTorch
  • Git
  • CI/CD
  • Nextflow
  • Docker
  • ML artifact tracking
  • Flow cytometry
  • Batch-effect harmonisation

Nice to have

  • Clinical trial datasets
  • MedDev ML regulations
  • Transplant immunology
  • Oncology
  • Hematologic malignancies

Qualifications

  • Master’s or Ph.D. in Bioinformatics, Statistics, Computational Biology, Computer Science, Bioengineering, or a related quantitative field
  • 3+ years of professional experience handling flow cytometry high-throughput data

Benefits

  • Competitive salary
  • Company bonus scheme
  • Pension
  • Health insurance
  • Life assurance
  • Income protection

About the Company

IMU Biosciences has developed proprietary platform technologies that generate and translate vast system-level immune data into actionable insights and tools to drive the development of precision medicines. The company leverages advanced immune profiling with proprietary AI and machine learning analytics to uncover novel clinical immune signatures.

Bioinformatics Software Engineer at Imubiosciences · Grasshire