Computational design of biological experiments for model development

About the role

Inceptive is pioneering AI-designed drugs by training large-scale foundation models on diverse biological datasets. You will collaborate with AI researchers and biologists to characterize model behavior, develop evaluations, and generate insights that guide data strategy and experimental priorities. This role involves designing rigorous experiments to understand the capabilities and limitations of biological foundation models.

Responsibilities

• Investigate how model performance changes with data quantity, data quality, dataset composition, and training methodology
• Develop biologically meaningful evaluations and benchmarks that measure progress toward therapeutic design objectives
• Design and execute rigorous experiments to understand the behavior, capabilities, and limitations of biological foundation models
• Identify sources of potential artifacts, bias, and noise in biological datasets
• Identify promising biological datasets for model training and evaluation, and develop computational pipelines for preprocessing, quality control, and exploratory analysis
• Design studies, in silico or in the lab, that reveal what models have learned and which biological signals drive model behavior
• Work with biologists to formulate hypotheses and translate biological questions into measurable machine learning experiments
• Partner with AI researchers and engineers to prioritize research directions, data collection efforts, and model improvements
• Analyze, visualize, and communicate experimental findings to inform decisions across teams

Required skills

• Computational biology
• Statistics
• Machine learning
• Python
• Scientific computing
• High throughput sequencing
• Generative AI
• Representation learning

Nice to have

• Biostatistics

Qualifications

• PhD in computational biology, statistics, physics, machine learning, or a related quantitative discipline
• Equivalent practical experience

Benefits

• 30 days paid vacation
• Health insurance
• 401K with company match
• Direktversicherung
• Quarterly company-wide retreats
• Monthly wellness benefit
• Learning & Development budget
• Buddy program

About the Company

Inceptive is creating tools to develop powerful biological software for the rational design of novel, broadly accessible medicines and biotechnologies. The team brings together expertise in molecular biology, machine learning, and software engineering, fostering an antedisciplinary culture centered around growth, learning, and discovery.