Computational design of biological experiments for model development

About the role

Inceptive is pioneering AI-designed drugs by training large-scale foundation models on biological datasets. This role involves collaborating with AI researchers and biologists to characterize model behavior, develop evaluations, and guide data strategy through rigorous experimentation. You will help translate biological questions into measurable machine learning experiments to advance therapeutic design objectives.

Responsibilities

• Investigate how model performance changes with data quantity, quality, composition, and training methodology.
• Develop biologically meaningful evaluations and benchmarks to measure progress toward therapeutic design objectives.
• Design and execute rigorous experiments to understand the behavior, capabilities, and limitations of biological foundation models.
• Identify sources of potential artifacts, bias, and noise in biological datasets.
• Identify promising biological datasets for model training and evaluation, and develop computational pipelines for preprocessing and analysis.
• Design in silico or lab-based studies to reveal what models have learned and which biological signals drive behavior.
• Work with biologists to formulate hypotheses and translate biological questions into measurable machine learning experiments.
• Partner with AI researchers and engineers to prioritize research directions, data collection, and model improvements.

Required skills

• Computational biology
• Statistics
• Machine learning
• Python
• High throughput sequencing
• Generative AI
• Representation learning
• Scientific computing

Nice to have

• Biostatistics

Qualifications

• PhD in computational biology, statistics, physics, machine learning, or a related quantitative discipline
• Equivalent practical experience with a record of publications or open source tooling

Benefits

• 30 days paid vacation
• Health insurance
• 401K with company match
• Direktversicherung
• Quarterly company-wide retreats
• Monthly wellness benefit
• Travel budget for office visits
• Learning and development budget

About the Company

Inceptive is creating tools to develop powerful biological software for the rational design of novel, broadly accessible medicines and biotechnologies. The team brings together expertise in molecular biology, machine learning, and software engineering, fostering an antedisciplinary culture centered around growth, learning, and discovery.